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PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling It seems to interact in

SKU: 88525901458

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PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling It seems to interact indisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:

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Description

It seems to interact in a multiprotein complex with RbAp48 and HDAC3

Several transcript variants encoding different isoforms have been found for PPP1R12A

The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit

Several alternatively spliced transcript variants of this gene have been described| but their biological validity has not been determined

suggesting that it may also play an important role in cells undergoing rapid cell division

PLXB1 Polyclonal Antibody, 100ul Electrophoresis & Labeling It seems to interact indisease: Overexpressed and constitutively tyrosine phosphorylated in colon, liver, pancreas and gastric carcinoma cell lines. Overexpression increases MET activation and promotes invasive growth.,Receptor for SEMA4D. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration.,PTM: Phosphorylated on tyrosine residues by ERBB2 and MET upon SEMA4D binding.,PTM:

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