Tsg 101 Polyclonal Antibody, 50ul Hepatocytes XIAP encodes E3 ubiquitin-protein ligase

XIAP encodes E3 ubiquitin-protein ligase XIAP that belongs to a family of apoptotic suppressor proteins

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This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls

48 (DFNB48)

Several variants encoding a few different isoforms exist| and at least one isoform appears to be a secreted protein

Tsg 101 Polyclonal Antibody, 50ul Hepatocytes XIAP encodes E3 ubiquitin-protein ligaseThe protein encoded by TSG101 (tumor susceptibility 101) belongs to a group of apparently inactive homologs of ubiquitin conjugating enzymes. The gene product contains a coiled coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady state expression of this tumor susceptibility gene appears to