PRP8 Polyclonal Antibody, 100ul Protein Expression The heat shock protein family

The heat shock protein family B (small) member 1 encoded by HSPB1 is induced by environmental stress and developmental changes

This gene likely encodes a member of the complexin family

and cortical function

This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation

Alternative splicing of transcripts from this gene results in multiple transcript variants

PRP8 Polyclonal Antibody, 100ul Protein Expression The heat shock protein familyPre mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2 and U12 dependent spliceosomes, and found to be essential for the catalytic step II in pre mRNA splicing process. It contains several WD repeats, which function in protein protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis