Ksr-1 Polyclonal Antibody, 50ul Protein Expression Nonsyndromic hearing impairment is associated

Nonsyndromic hearing impairment is associated with a mutation in this gene

Activates the JUN N-terminal pathway

tissue specificity:Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells

and are also associated with response to the antidepressant citalopram in patients with major depressive disorder (MDD)

This protein may function in vesicle trafficking| membrane fusion| protein complex assembly and cell motility

Ksr-1 Polyclonal Antibody, 50ul Protein Expression Nonsyndromic hearing impairment is associatedKSR1 (kinase supressor of Ras) was identified from a genetic screen in Drosophila and C. elegans as a component of the Ras signaling pathway. KSR1 has a putative carboxy terminal kinase domain that lacks a key Lys residue for phospho group transfer. Although reports indicate that ceramide and EGF activate KSR1, other evidence demonstrates that KSR1 regulates Raf in a kinase independent manner. It is now widely accepted that KSR1 functions as a