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CD27 Polyclonal Antibody, 20ul Centrifuges 118A>G allele has been associated

SKU: 8895414658

4.7
PLN97.20 PLN121.20

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CD27 Polyclonal Antibody, 20ul Centrifuges 118A>G allele has been associatedThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is required for generation and long term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF kappaB and MAPK8 JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this

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Description

118A>G allele has been associated with opioid and alcohol addiction and variations in pain sensitivity but evidence for it having a causal role is conflicting

Both TAL1 and LMO2 have been associated with T-cell acute lymphoblastic leukemia (T-ALL)

It is predicted to have a cytoplasmic C-terminus| 13 transmembrane domains| and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus

has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation

the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2

CD27 Polyclonal Antibody, 20ul Centrifuges 118A>G allele has been associatedThe protein encoded by this gene is a member of the TNF receptor superfamily. This receptor is required for generation and long term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF kappaB and MAPK8 JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this

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