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TRAIP Rabbit Polyclonal Antibody, 100ul Primary Antibodies Mutations of this gene have

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TRAIP Rabbit Polyclonal Antibody, 100ul Primary Antibodies Mutations of this gene haveThis gene encodes a protein that contains an N terminal RING finger motif and a putative coiled coil domain. A similar murine protein interacts with TNFR associated factor 1 (TRAF1) TNFR associated factor 2 (TRAF2) and cylindromatosis. The interaction with TRAF2 inhibits TRAF2 mediated nuclear factor kappa B subunit 1 activation that is required for cell activation and protection against apoptosis.

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Description

Mutations of this gene have been associated with branchiootorenal dysplasia syndrome

An N-terminal amphipathic helix

pseudohermaphroditism

Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin| a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth

this mRNA is expressed only in testis

TRAIP Rabbit Polyclonal Antibody, 100ul Primary Antibodies Mutations of this gene haveThis gene encodes a protein that contains an N terminal RING finger motif and a putative coiled coil domain. A similar murine protein interacts with TNFR associated factor 1 (TRAF1) TNFR associated factor 2 (TRAF2) and cylindromatosis. The interaction with TRAF2 inhibits TRAF2 mediated nuclear factor kappa B subunit 1 activation that is required for cell activation and protection against apoptosis.

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