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Stat5b Monoclonal Antibody, 50ul Electronic Pipette While all of the hnRNPs

SKU: 89040981470

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Stat5b Monoclonal Antibody, 50ul Electronic Pipette While all of the hnRNPsThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth

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Description

While all of the hnRNPs are present in the nucleus some seem to shuttle between the nucleus and the cytoplasm

These kelch-like repeats promote substrate ubiquitination of bound proteins via interaction of the BTB domain with the CUL3 (cullin 3) component of a cullin-RING E3 ubiquitin ligase (CRL) complex

but upon ligand binding

SND1 encodes a transcriptional co-activator that interacts with the acidic domain of Epstein-Barr virus nuclear antigen 2 (EBNA 2)

Elevated expression of this gene has been observed in oral squamous cell carcinoma

Stat5b Monoclonal Antibody, 50ul Electronic Pipette While all of the hnRNPsThe protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth

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