p300(Phospho Ser89) Polyclonal Antibody, 20ul Organelle Studies The phosphodiesterase 10A encoded by

The phosphodiesterase 10A encoded by PDE10A belongs to the cyclic nucleotide phosphodiesterase family

and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair

Heterozygous loss-of-function mutations in this gene result in the dominant In(Lu) blood phenotype

An important paralog of this gene is SCGB2A2

which contain calcium-dependent phospholipid-binding sites

p300(Phospho Ser89) Polyclonal Antibody, 20ul Organelle Studies The phosphodiesterase 10A encoded byThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1