p53R2 Polyclonal Antibody, 50ul Cell Separation and Collection 2001 [PubMed 11165019])

2001 [PubMed 11165019])

This gene encodes a member of the rhophilin family of Ras-homologous (Rho)-GTPase binding proteins

Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36

Each monomer of trimeric S protein is about 180 kDa

which have been implicated in the regulation of cytoskeletal dynamics

p53R2 Polyclonal Antibody, 50ul Cell Separation and Collection 2001 [PubMed 11165019])RRM2B encodes the small subunit of a p53 inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia 5, and mitochondrial