Shc Polyclonal Antibody, 50ul[BT-AP08289] Cell Proliferation Several isozymes of this gene

Several isozymes of this gene family exist in vertebrates

• Speed up to 15000rpm

possibly by inhibition of mRNA stabilization

There are a number of related genes present on chromosomes 20 and 22| and putative pseudogenes for this gene on chromosomes 2| 13| and 22

Rho family small GTPases

Shc Polyclonal Antibody, 50ul[BT-AP08289] Cell Proliferation Several isozymes of this geneSHC1 (SHC adaptor protein 1) encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways, the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms, p52Shc and p46Shc, link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in