MARH9 Polyclonal Antibody, 20ul Antisense Oligonucleotides This gene encodes a protein

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF| and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II)| making it available for initiation of gene expression

as only a minority of individuals showed biased expression from the maternal allele (PMID: 8267611)

It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage

ITPR1 (inositol 1

an area known to be lost in hereditary renal tumors

MARH9 Polyclonal Antibody, 20ul Antisense Oligonucleotides This gene encodes a proteinMARCH9 is a member of the MARCH family of membrane bound E3 ubiquitin ligases (EC 6. 3. 2. 19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment (Bartee et al., 2004