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Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the founding

SKU: 89388664706

4.9
USD185.00 USD226.00

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Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the foundingThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

NBL1 product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

allowing safe and aseptic sampling

The protein encoded by this intronless gene belongs to the claudin family

DNA repair associated) combines with other tumor suppressors

Phospho-Akt1 (T72) Polyclonal Antibody, 50ul Plasmid Preparation NBL1 product is the foundingThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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