GLCNE Polyclonal Antibody, 20ul Polyclonal Antibodies The encoded kinase may activate

The encoded kinase may activate cyclin-dependent kinase 2 and is involved in cell growth

Six alternatively spliced transcript variants encoding different isoforms have been reported

and are also necessary for the uptake of cytotoxic nucleosides used for cancer and viral chemotherapies

upon ligand binding

the full-length natures of only two have been described to date

GLCNE Polyclonal Antibody, 20ul Polyclonal Antibodies The encoded kinase may activateThe glucosamine (UDP N acetyl) 2 epimerase N acetylmannosamine kinase encoded by GNE is a bifunctional enzyme that initiates and regulates the biosynthesis of N acetylneuraminic acid (NeuAc), a precursor of sialic acids. It is a rate limiting enzyme in the sialic acid biosynthetic pathway. Sialic acid modification of cell surface molecules is crucial for their function in many biologic processes, including cell adhesion and signal transduction.