Phospho PKC theta (Y90) Rabbit Polyclonal Antibody, 50ul Bottles Defects in this gene are
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Phospho PKC theta (Y90) Rabbit Polyclonal Antibody, 50ul Bottles Defects in this gene areCatalytic activity: ATP + a protein = ADP + a phosphoprotein. cofactor: Magnesium. The C1 domain containing the phorbol ester DAG type region 1 (C1A) and 2 (C1B) is the diacylglycerol sensor and the C2 domain is a non calcium binding domain. enzyme regulation: Three specific sites; Thr 538 (activation loop of the kinase domain) Ser 676 (turn motif) and Ser 695 (hydrophobic region) need to be phosphorylated for its full activation. PKC is activated by
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