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Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos This gene and other MAGEB

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Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos This gene and other MAGEBThe protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

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Description

This gene and other MAGEB members are clustered on chromosome Xp22-p21

The ninjurin protein is upregulated after nerve injury both in dorsal root ganglion neurons and in Schwann cells (Araki and Milbrandt

The proteins in this family contain a domain that gives the kinase the ability to determine its own scaffold to control the effects of their kinase activities

and is likely to be important in developmental processes and cell communication

The encoded protein plays a role in the formation of noncentrosomal microtubules

Arylsulfatase A Polyclonal Antibody, 50ul sgRNA Oligos This gene and other MAGEBThe protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.

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