Human Junctional Adhesion Molecule A, F11R ELISA Kit, 5*96T ROS/Nitric Oxide Detection Isoform 2 is an antagonist

Isoform 2 is an antagonist of isoform 1

|enzyme regulation:Strongly inhibited by TIMP-2| TIMP-3 and TIMP-4| while TIMP-1 is less efficient

via MAPK1/3 and PI3K-AKT1 pathways (By similarity) (PubMed: 17344214)

Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) preferentially as susbstrate: shows a higher activity towards an acyl-CoA substrate with a double bond at the delta-9 position (9Z) than towards saturated acyl-CoA or an unsaturated acyl-CoA with a double bond at the delta-7 (7Z) or delta-11 (11Z) positions (PubMed: 11294643

Pseudogenes have been identified on chromosomes X and 6

Human Junctional Adhesion Molecule A, F11R ELISA Kit, 5*96T ROS/Nitric Oxide Detection Isoform 2 is an antagonist