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UBE1L Polyclonal Antibody, 50ul Drying & Desiccation NRP2 encodes a member of

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UBE1L Polyclonal Antibody, 50ul Drying & Desiccation NRP2 encodes a member ofThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes, or E1s, ubiquitin conjugating enzymes, or E2s, and ubiquitin protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin activating enzyme family. The encoded enzyme is a retinoid target that triggers

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Description

NRP2 encodes a member of the neuropilin family of receptor proteins

This protein and ATM share similarity with Schizosaccharomyces pombe rad3| a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage

Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix

Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene

UBE1L Polyclonal Antibody, 50ul Drying & Desiccation NRP2 encodes a member ofThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin activating enzymes, or E1s, ubiquitin conjugating enzymes, or E2s, and ubiquitin protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin activating enzyme family. The encoded enzyme is a retinoid target that triggers

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