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ROR Alpha Polyclonal Antibody, 100ul Modification Enzymes Expression of this protein in

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ROR Alpha Polyclonal Antibody, 100ul Modification Enzymes Expression of this protein inNuclear receptor ROR alpha encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23 2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23 1, the product of a tumor metastasis suppressor

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Description

Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions

This encoded protein can form a complex with the Golgi matrix protein GOLGA2

Mutations in this gene cause congenital adrenal hyperplasia due to 11-beta-hydroxylase deficiency

Three alternatively spliced transcript variants encoding different isoforms have been found for this gene

interacting with nuclear transcription factor Y to activate UPR target genes

ROR Alpha Polyclonal Antibody, 100ul Modification Enzymes Expression of this protein inNuclear receptor ROR alpha encoded by RORA is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23 2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23 1, the product of a tumor metastasis suppressor

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