APOB Rabbit Polyclonal Antibody, 20ul Cell Biology Mutations in this gene are

Mutations in this gene are associated with Griscelli syndrome type 2

although its exact role in oncogenesis has not been demonstrated

Alternatively spliced transcript variants encoding multiple isoforms have been observed for TIE1

a single transmembrane domain

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors| including estrogen receptor alpha| nuclear respiratory factor 1| and glucocorticoid receptor

APOB Rabbit Polyclonal Antibody, 20ul Cell Biology Mutations in this gene areThis gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms apoB 48 and apoB 100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single very long mRNA. The two isoforms share a common N terminal sequence. The shorter apoB 48 protein is produced after RNA editing of the