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Aven Polyclonal Antibody, 100ul Inoculating Loops/Needles A folding variant of alpha-lactalbumin

SKU: 90293132828

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Aven Polyclonal Antibody, 100ul Inoculating Loops/Needles A folding variant of alpha-lactalbuminAVEN, a cell death regulator, is an important signal inducer in acute leuke mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf 1 mediated apoptosis by interfering with Apaf 1's ability to self associate. Bcl 2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be

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Description

A folding variant of alpha-lactalbumin

the encoded protein is associated with the actin cytoskeleton and focal adhesions and promotes developing focal adhesion elongation

This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein

Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor

The encoded protein is only active when it is phosphorylated

Aven Polyclonal Antibody, 100ul Inoculating Loops/Needles A folding variant of alpha-lactalbuminAVEN, a cell death regulator, is an important signal inducer in acute leuke mias. AVEN is a highly conserved peripheral membrane protein that protects the cell against the proteolytic activation of caspases as well as Apaf 1 mediated apoptosis by interfering with Apaf 1's ability to self associate. Bcl 2 and Bad also interact with AVEN to prevent apoptosis. AVEN is highly expressed in ovary, heart, thymus, spleen, testis and colon, but can also be

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