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p27(Phospho Thr157) Polyclonal Antibody, 50ul Drying & Desiccation Selenophosphate is the selenium donor

SKU: 9052130586

4.3
EUR142.00 EUR163.00

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p27(Phospho Thr157) Polyclonal Antibody, 50ul Drying & Desiccation Selenophosphate is the selenium donorThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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Description

Selenophosphate is the selenium donor used to synthesize selenocysteine| which is co-translationally incorporated into selenoproteins at in-frame UGA codons

and which specifically associates with spliced mRNA and not with unspliced pre-mRNA

Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly

The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling

the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2

p27(Phospho Thr157) Polyclonal Antibody, 50ul Drying & Desiccation Selenophosphate is the selenium donorThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from

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