UNC5B Polyclonal Antibody, 20ul Protein Research The human genome contains five

The human genome contains five CD1 family genes organized in a cluster on chromosome 1

Alternative splicing results in multiple transcript variants and protein isoforms

Mutations in this gene have been associated with X-linked mental retardation

The axonemal dyneins| found in cilia and flagella| are components of the outer and inner dynein arms attached to the peripheral microtubule doublets

The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains| which bind microtubules

UNC5B Polyclonal Antibody, 20ul Protein Research The human genome contains fiveThis gene encodes a member of the netrin family of receptors. This particular protein mediates the repulsive effect of netrin 1 and is a vascular netrin receptor. This encoded protein is also in a group of proteins called dependence receptors (DpRs) which are involved in pro and anti apoptotic processes. Many DpRs are involved in embryogenesis and in cancer progression. Two alternatively spliced transcript variants have been described for this gene.