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Srb7 Polyclonal Antibody, 50ul Variant Libraries The protein encoded by this

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Srb7 Polyclonal Antibody, 50ul Variant Libraries The protein encoded by thisMED21 (mediator complex subunit 21) encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of MED21 is located on chromosome 8. Alternative splicing results in multiple transcript variants.

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Description

The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17

Constitutive activation of this gene caused either by somatic mutations| or genomic duplications of regions that include this gene| have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome

was thought to exist

|Belongs to the histone deacetylase family

also known as MANSC3

Srb7 Polyclonal Antibody, 50ul Variant Libraries The protein encoded by thisMED21 (mediator complex subunit 21) encodes a member of the mediator complex subunit 21 family. The encoded protein interacts with the human RNA polymerase II holoenzyme and is involved in transcriptional regulation of RNA polymerase II transcribed genes. A pseudogene of MED21 is located on chromosome 8. Alternative splicing results in multiple transcript variants.

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