SLP-76(Phospho Tyr128) Polyclonal Antibody, 100ul Plates & Dishes It assembles membrane vesicles before

It assembles membrane vesicles before the matrix proteins are translocated

It possesses both activation and repression domains| and it can therefore have both positive and negative effects on the transcription of target genes

Alternate splicing results in multiple transcript variants encoding multiple isoforms

There are six pseudogenes of this gene found on chromosomes 2

Reduced expression of this gene and consequent caspase upregulation may be correlated with progression of Alzheimer's disease in human patients

SLP-76(Phospho Tyr128) Polyclonal Antibody, 100ul Plates & Dishes It assembles membrane vesicles beforeSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic