Cadherin-8 Polyclonal Antibody, 50ul Multiplex Immunoassays TIPRL is an inhibitory regulator

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA

and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake

Reduced expression of this gene results in an increase in GLUT4 levels at the plasma membrane| suggesting that this protein is important in intracellular retention of GLUT4 under basal conditions

including the BRCA1-A complex and the BRISC complex

Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes

Cadherin-8 Polyclonal Antibody, 50ul Multiplex Immunoassays TIPRL is an inhibitory regulatorCDH8 encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium dependent cell cell adhesion. Mature cadherin proteins are composed of a large N terminal extracellular domain, a single membrane spanning domain, and a small, highly conserved C terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity