JAK2 Polyclonal Antibody, 100ul[BT-AP04686] Monoclonal Antibodies Mutations in this gene are

Mutations in this gene are associated with osteoarthritis in humans

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors

The orthologous mouse protein has been shown to influence cytoskeletal organization and cell migration by binding to alpha-5-beta-1 integrin

Diseases associated with TRAK2 include amyotrophic lateral sclerosis 2

which may contribute to many overlapping functions of this cytokine and IL13

JAK2 Polyclonal Antibody, 100ul[BT-AP04686] Monoclonal Antibodies Mutations in this gene areTyrosine protein kinase JAK2 is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.