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MARCKS(Phospho Ser163) Polyclonal Antibody, 100ul Metabolic enzymes The N-terminal nucleotide phosphate binding

SKU: 90786057325

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MARCKS(Phospho Ser163) Polyclonal Antibody, 100ul Metabolic enzymes The N-terminal nucleotide phosphate bindingThe protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

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Description

The N-terminal nucleotide phosphate binding region cAMP 1 has a much lower affinity for cAMP as compared to cAMP 2

RASD2 belongs to the Ras superfamily of small GTPases and is enriched in the striatum

binds to DNA and regulates the expression of genes involved in bile acid synthesis and transport

this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF

Freeman-Sheldon syndrome and Sheldon-Hall syndrome

MARCKS(Phospho Ser163) Polyclonal Antibody, 100ul Metabolic enzymes The N-terminal nucleotide phosphate bindingThe protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.

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