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EpoR(Phospho Tyr368) Polyclonal Antibody, 20ul Cryopreservation Two alternatively spliced transcript variants

SKU: 90836926187

4.9
USD97.20 USD144.20

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EpoR(Phospho Tyr368) Polyclonal Antibody, 20ul Cryopreservation Two alternatively spliced transcript variantsThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce

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Description

Two alternatively spliced transcript variants that encode different proteins have been described for this gene

the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM)

aspartate transcarbamoylase

The sphingosine-1-phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells

The type II isoform encoded by this gene

EpoR(Phospho Tyr368) Polyclonal Antibody, 20ul Cryopreservation Two alternatively spliced transcript variantsThis gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras MAP kinase, phosphatidylinositol 3 kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce

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