WDFY1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges function:Transcriptional activator that binds to

function:Transcriptional activator that binds to the enhancer of the adenovirus E1A gene| the core-binding sequence is 5'[AC]GGA[AT]GT-3'

This protein is also involved in specification of neuronal cell fates

In addition| a SNP in this gene is responsible for determination of human earwax type

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

Both calcium/calmodulin and protein phosphorylation mechanisms control its activity

WDFY1 Polyclonal Antibody, 50ul High Speed Micro-Centrifuges function:Transcriptional activator that binds toThe protein encoded by this gene is a phosphatidylinositol 3 phosphate binding protein, which contains a FYVE zinc finger domain and multiple WD 40 repeat domains. When exogenously expressed, it localizes to early endosomes. Mutagenesis analysis demonstrates that this endosomal localization is mediated by the FYVE domain.