Human Gasdermin D, GSDMD ELISA Kit, 96T Microplate Mixer it enhances CD3-triggered activation of

it enhances CD3-triggered activation of T-cells and subsequent IL2 production (By similarity)

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases

This protein forms a receptor complex with interleukine 10 receptor

Latency-associated Peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains remain non-covalently linked rendering TGF-beta-2 inactive during storage in extracellular matrix (By similarity)

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Human Gasdermin D, GSDMD ELISA Kit, 96T Microplate Mixer it enhances CD3-triggered activation of[Gasdermin D]: Precursor of a pore forming protein that plays a key role in host defense against pathogen infection and danger signals (PubMed: 26375003, PubMed: 26375259, PubMed: 27281216). This form constitutes the precursor of the pore forming protein: upon cleavage, the released N terminal moiety (Gasdermin D, N terminal) binds to membranes and forms pores, triggering pyroptosis (PubMed: 26375003, PubMed: 26375259, PubMed: 27281216). [Gasdermin D,