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KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification This intronless gene HSPA1A(heat shock

SKU: 91064631987

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KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification This intronless gene HSPA1A(heat shockKANK2 encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.

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Description

This intronless gene HSPA1A(heat shock protein family A(Hsp70) member 1A) encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family

Crosslink of this receptor protein on the surface of monocytes has been shown to induce calcium flux and secretion of several proinflammatory cytokines

It is thought that this protein may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein

This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes

The encoded protein is a transcription factor important for the development of the renal and urogenital systems

KANK2 Polyclonal Antibody, 20ul Protein Post-translational Modification This intronless gene HSPA1A(heat shockKANK2 encodes a member of the KN motif and ankyrin repeat domains (KANK) family of proteins, which play a role in cytoskeletal formation by regulating actin polymerization. The encoded protein functions in the sequestration of steroid receptor coactivators and possibly other proteins. Mutations in this gene are associated with impaired kidney podocyte function and nephrotic syndrome, and keratoderma and woolly hair.

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