PGFRL Polyclonal Antibody, 50ul Antibody Humanization The encoded protein (CD300 molecule

The encoded protein (CD300 molecule like family member f) is an inhibitory receptor

Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex| leading to epilepsy| mental retardation| subcortical band heterotopia ("double cortex" syndrome) in females and lissencephaly ("smooth brain&quo

This gene encodes a DNA topoisomerase

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Mutations in this gene are associated with hypogonadism which is characterized by infertility and pseudohermaphroditism

PGFRL Polyclonal Antibody, 50ul Antibody Humanization The encoded protein (CD300 moleculeThis gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non small cell lung cancers. This suggests this gene product may function as a tumor suppressor.