Caldesmon Polyclonal Antibody, 100ul[BT-AP01120] Sample Library Tubes Alternative splicing is the basis

Alternative splicing is the basis for the structural and functional diversity of this protein

which is required for normal postnatal growth and survival

The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions

leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene

The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development

Caldesmon Polyclonal Antibody, 100ul[BT-AP01120] Sample Library Tubes Alternative splicing is the basisCALD1 (caldesmon 1) encodes a calmodulin and actin binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+) calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+) dependent inhibition of