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AZI1 Polyclonal Antibody, 50ul Apoptosis & Autophagy The type I hair keratins

SKU: 91318643956

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AZI1 Polyclonal Antibody, 50ul Apoptosis & Autophagy The type I hair keratinsAZI1, also known as 5 azacytidine induced protein 1, is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on

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Description

The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription

Loss of the encoded protein is associated with bleeding disorder platelet-type 9

Autoantibodies against the encoded protein may be markers for scleroderma and Crohn's disease

Different dimer combinations act as transcriptional activators or repressors| respectively

Calreticulin binds to the synthetic peptide KLGFFKR

AZI1 Polyclonal Antibody, 50ul Apoptosis & Autophagy The type I hair keratinsAZI1, also known as 5 azacytidine induced protein 1, is a 1,083 amino acid protein that may play a role in spermatogenesis. AZI1 is most highly expressed in spinal cord, followed by testis, ovary, amygdala, cerebellum and thalamus. Low expression is present in other adult and fetal tissues and specific adult brain regions. AZl1 gene transcription begins in pachytene spermatocytes and expression of the gene is induced in cultivated fibroblasts on

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