PARP-2 Polyclonal Antibody, 50ul Cell Culture Flasks Defects in this factor lead

Defects in this factor lead to Rosenthal syndrome| a blood coagulation abnormality

It localizes primarily within subnuclear foci associated with the nuclear matrix

protein expression

Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2

on the same chromosome several hundred kilobases away (PMID: 21336277 and 22928559)

PARP-2 Polyclonal Antibody, 50ul Cell Culture Flasks Defects in this factor leadPARP2 encodes poly(ADP ribosyl)transferase like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP ribosyl)ation reaction. Poly [ADP ribose] polymerase 2 has a catalytic domain which is homologous to that of poly (ADP ribosyl) transferase, but lacks an N terminal DNA binding domain which activates the C terminal catalytic domain of poly (ADP ribosyl) transferase. The basic residues within the N terminal region of this