NT5C3 Polyclonal Antibody, 100ul Gloves Rho guanine nucleotide exchange factor

Rho guanine nucleotide exchange factor 2 may form complex with G proteins and stimulate rho-dependent signals

This protein binds to the SH3 domains of GRB2| an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras)| via its C-terminal proline-rich sequences| and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2

A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines

this protein is also synthesized in peripheral tissues

Flavin-containing monooxygenases (FMO) are an important class of drug-metabolizing enzymes that catalyze the NADPH-dependent oxygenation of various nitrogen-

NT5C3 Polyclonal Antibody, 100ul Gloves Rho guanine nucleotide exchange factorNT5C3A (5' nucleotidase, cytosolic IIIA) encodes a member of the 5' nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5' monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. Mutations in NT5C3A are a cause of hemolytic anemia due to uridine 5 prime monophosphate hydrolase deficiency. Alternatively spliced transcript