TBX15 Polyclonal Antibody, 20ul Culture Plate Inserts active Rb proteins are hypophosphorylated

active Rb proteins are hypophosphorylated and bind to E2F transcription factors to repress transcription and inhibit cell cycle progression

EPS8L3 (EPS8 like 3) encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8)

The encoded protein contains a large hydrophobic extracellular domain and a smaller basic intracellular domain

This gene has been implicated in the pathogenesis of several autoimmune diseases

|subcellular location:When phosphorylated| translocated from nucleus to cytoplasm

TBX15 Polyclonal Antibody, 20ul Culture Plate Inserts active Rb proteins are hypophosphorylatedThis gene belongs to the T box family of genes, which encode a phylogenetically conserved family of transcription factors that regulate a variety of developmental processes. All these genes contain a common T box DNA binding domain. Mutations in this gene are associated with Cousin syndrome.