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PICAL Polyclonal Antibody, 100ul Live Cell Imaging The PGBD proteins appear to

SKU: 91557316272

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PICAL Polyclonal Antibody, 100ul Live Cell Imaging The PGBD proteins appear toThis gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated pit formation and clathrin vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2 dependent clathrin mediated endocytosis at the neuromuscular junction. A chromosomal translocation

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Description

The PGBD proteins appear to be novel| with no obvious relationship to other transposases| or other known protein families

The genes responsible likely encode proteins involved in the degradation of post-translationally modified proteins in lysosomes

Involved in protein ubiquitination

This gene encodes a member of the WWC family of proteins| which also includes the WWC1 (KIBRA) gene product and the WWC2 gene product

MCU (mitochondrial calcium uniporter) encodes a calcium transporter that localizes to the mitochondrial inner membrane

PICAL Polyclonal Antibody, 100ul Live Cell Imaging The PGBD proteins appear toThis gene encodes a clathrin assembly protein, which recruits clathrin and adaptor protein complex 2 (AP2) to cell membranes at sites of coated pit formation and clathrin vesicle assembly. The protein may be required to determine the amount of membrane to be recycled, possibly by regulating the size of the clathrin cage. The protein is involved in AP2 dependent clathrin mediated endocytosis at the neuromuscular junction. A chromosomal translocation

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