TPH2 Polyclonal Antibody, 100ul Peptide Modification is present in 3 forms

is present in 3 forms with respect to ability to bind interleukin 2

and all arranged to form a ligand-gated ion channel

tumor suppressor mediated growth arrest and replicative senescence

The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein

A 117 kb microdeletion at the 5' end of the HOXD gene cluster| which includes this gene and the HOXD9-HOXD13 genes| causes synpolydactyly| a dominantly inherited disease resulting in limb malformation

TPH2 Polyclonal Antibody, 100ul Peptide Modification is present in 3 formsTPH2 encodes a member of the pterin dependent aromatic acid hydroxylase family. The tryptophan hydroxylase 2 catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression.