Stat3 Polyclonal Antibody, 20ul[BT-AP01663] Subcellular Fractions |tissue specificity:Expressed principally in liver

|tissue specificity:Expressed principally in liver

MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins

Acts as a coactivator

Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome

and it is involved in photoreceptor cell maintenance

Stat3 Polyclonal Antibody, 20ul[BT-AP01663] Subcellular Fractions |tissue specificity:Expressed principally in liverThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors STAT family members are phosphorylated by the receptor associated kinases and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs EGF IL5 IL6 HGF LIF and BMP2.