DOCK 2 Polyclonal Antibody, 50ul Drug Development and Evaluation which is atypical of CNC-bZip

which is atypical of CNC-bZip family members

and is thought to be involved in mesoderm segmentation

This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing

The encoded protein acts as a transcription factor and may be autoregulatory

this protein is localized to the cytoplasm of primary spermatocytes

DOCK 2 Polyclonal Antibody, 50ul Drug Development and Evaluation which is atypical of CNC-bZipDedicator of cytokinesis protein 2 encoded by DOCK2 belongs to the CDM protein family. It is specifically expressed in hematopoietic cells, predominantly in the peripheral blood leukocytes, and is involved in remodeling of the actin cytoskeleton required for lymphocyte migration, through the activation of RAC. Mice lacking this gene show a severe impairment in the migration and homing of lymphocytes. These mutant mice also exhibited long term survival