NPC2 Rabbit Polyclonal Antibody, 20ul Immune Cell Analysis Despite the gene family name

Despite the gene family name similarity

Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins

Pseudogenes of this gene are located on the long arm of chromosome 13 and the short arm of chromosome 19

The axonemal dyneins| found in cilia and flagella| are components of the outer and inner dynein arms attached to the peripheral microtubule doublets

subcellular location:Shuttles between nucleus and cytoplasm

NPC2 Rabbit Polyclonal Antibody, 20ul Immune Cell Analysis Despite the gene family nameThis gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal lysosomal system. Mutations in this gene have been associated with Niemann Pick disease type C2 and frontal lobe atrophy.