CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries EPHB6 encodes a member of

EPHB6 encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins

HMGB1 encodes a protein that belongs to the High Mobility Group-box superfamily

SFSWAP encodes a human homolog of Drosophila splicing regulatory protein

Mutations in this gene result in one form of autosomal dominant hearing impairment

It is also found to be expressed in lipogenic breast cancers| which suggests a role in controlling tumor lipid metabolism

CHD8 Polyclonal Antibody, 50ul Human Genome Knockout Libraries EPHB6 encodes a member ofThis gene encodes a DNA helicase that functions as a transcription repressor by remodeling chromatin structure. It binds beta catenin and negatively regulates Wnt signaling pathway, which plays a pivotal role in vertebrate early development and morphogenesis. Mice lacking this gene exhibit early embryonic death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.