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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 50ul Glassware Sets It is a member of

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Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 50ul Glassware Sets It is a member ofATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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Description

It is a member of the MADS (MCM1

activate mitogen-activated protein kinase (MAPK)

PARD6B is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain

the N-terminal region contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues

A mutation in this gene has been reported to be associated with hereditary spastic paraplegia| however the pathogenicity of the mutation| which may simply represent a polymorphism| is unclear

Phospho-ATP-citrate synthase (S455) Polyclonal Antibody, 50ul Glassware Sets It is a member ofATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl CoA, serves several important biosynthetic pathways, including lipogenesis

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