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Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL)

which suggests the encoded protein may be a component of the 40S ribosomal subunit

The activation is rapid and specific

The remaining transcript includes an alternate first exon located 20 Kb upstream of the remainder of the gene

MTCH1 Rabbit Polyclonal Antibody, 100ul Roller Bottles Upgrade your MX-M Microplate MixeThis gene encodes a member of the mitochondrial carrier family. The encoded protein is localized to the mitochondrion inner membrane and induces apoptosis independent of the proapoptotic proteins Bax and Bak. Pseudogenes on chromosomes 6 and 11 have been identified for this gene. Alternatively spliced transcript variants encoding multiple isoforms have been observed.