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Dok-7 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This gene is a MAGE-B

SKU: 92622715787

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Dok-7 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This gene is a MAGE-BThe docking protein 7 encoded by DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle specific receptor kinase. Mutations in DOK7 are a cause of familial limb girdle myasthenia autosomal

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Description

This gene is a MAGE-B subfamily member of the MAGE gene family

which is a huntingtin binding protein that may function in vesicle trafficking

This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA

while mutant homozygotes are normal

This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins

Dok-7 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This gene is a MAGE-BThe docking protein 7 encoded by DOK7 is essential for neuromuscular synaptogenesis. The protein functions in aneural activation of muscle specific receptor kinase, which is required for postsynaptic differentiation, and in the subsequent clustering of the acetylcholine receptor in myotubes. This protein can also induce autophosphorylation of muscle specific receptor kinase. Mutations in DOK7 are a cause of familial limb girdle myasthenia autosomal

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