DMD Polyclonal Antibody, 100ul Custom Peptide Synthesis APC encodes a tumor suppressor

APC encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway

It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development

This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation

|GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6)

Mutations in this gene are associated with susceptibility to essential hypertension

DMD Polyclonal Antibody, 100ul Custom Peptide Synthesis APC encodes a tumor suppressorThe dystrophin gene is the largest gene found in nature, measuring 2. 4 Mb. The gene was identified through a positional cloning approach, targeted at the isolation of the gene responsible for Duchenne (DMD) and Becker (BMD) Muscular Dystrophies. DMD is a recessive, fatal, X linked disorder occurring at a frequency of about 1 in 3,500 new born males. BMD is a milder allelic form. In general, DMD patients carry mutations which cause premature