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SEN15 Rabbit Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene are

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SEN15 Rabbit Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene areThis gene encodes a subunit of the tRNA splicing endonuclease which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene on chromosome 17.

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Description

Mutations in this gene are associated with the French-Canadian type of Leigh syndrome

This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells

This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily

which has been shown to be essential for development of the heart-like dorsal vessel

cerebrovascular disease

SEN15 Rabbit Polyclonal Antibody, 20ul Electronic Pipette Mutations in this gene areThis gene encodes a subunit of the tRNA splicing endonuclease which catalyzes the removal of introns from tRNA precursors. Alternative splicing results in multiple transcript variants. There is a pseudogene of this gene on chromosome 17.

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