Porcine Caspase-3, CASP3 ELISA Kit, 96T Cell Culture Plates The encoded protein is a

The encoded protein is a glycosylphosphatidylinositol-anchored protein that is a member of the lymphocyte antigen 6 (Ly6) family

This gene encodes a protein containing a lines-like domain

Gene Ontology (GO) annotations related to this gene include 4 iron

FASTKD3 encodes a member of a small family of Fas-activated serine/threonine kinase domain (FASTKD) containing proteins that share an amino terminal mitochondrial targeting domain and multiple carboxy terminal FAST domains as well as a putative RNA-binding RAP domain

May act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity

Porcine Caspase-3, CASP3 ELISA Kit, 96T Cell Culture Plates The encoded protein is aInvolved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP ribose) polymerase (PARP) at a '216 Asp Gly 217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix loop helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase 6, 7 and 9. Involved in the cleavage of huntingtin.