Nibrin(Phospho Ser278) Polyclonal Antibody, 20ul Multiplex Immunoassays which are auxiliary proteins associating

which are auxiliary proteins associating with functional Kv-alpha subunits

PBK (PDZ binding kinase) encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family

and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1

The encoded protein

which are required for its enzymatic function

Nibrin(Phospho Ser278) Polyclonal Antibody, 20ul Multiplex Immunoassays which are auxiliary proteins associatingMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint